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update #1: upstream accepted my patch, so the next tmux release will provide window-status-alert-{attr,fg,bg} Only difference is the use of alert instead of flagged. It sounds better anyway  I’ll adjust my patch on 1.2 as well 
update #2 [2010/05/17]: uploaded my updated config file, now using ` as my prefix key
I gave tmux a try yesterday.
Clean config file, thorough documentation and a few nice touches here and there (i.e. better, persistent window splitting) make it a nice alternative to screen, but the biggest difference lies in memory usage. Screen can easily eat up to 40-50mb with just a few windows open, but tmux has yet to reach the 10mb mark!
You may argue that ram is cheap these days, but when you’re on a 360mb VPS ram matters 
I did find a few bugs/annoyances, for instance if you add set-option -g default-terminal “screen-256color” in your config file, tmux stops evaluating the #T variable.
I hacked my way out of this one by adding the following in my .bash_profile instead:

[[ $TERM == "screen" ]] && export -p TERM="screen-256color"

Turns out that’s not tmux’s fault but bash’s, I’ll have to create a patch for that as well  If you have the same issue, you can use the above hack as a temporary fix.

Also version 1.2 does not provide a way for you to customize the colors used on window titles with alerts (either monitored or when the bell is active), but I patched that and sent it upstream 
You can find an ebuild with the patch in my overlay, wirelay (layman -a wirelay  ).
The patch was accepted upstream so it’ll be in the next release.
My tmux looks like this:


and with some split panes:

finally, below is my (updated on 2010/05/17) tmux.conf config file, used in the above screenshots.
I decided to use ` as my prefix key, its really better than hitting ctrl-a all the time

# ` is an interesting key for a prefix
set-option -g prefix `
# set-option -g prefix C-a

unbind-key C-b
bind-key C-a last-window
bind-key ` last-window
bind-key a send-prefix

# we might need ` at some point, allow switching
# we can also send the prefix char with `-a
bind-key F11 set-option -g prefix C-a
bind-key F12 set-option -g prefix `

# 0 is too far from ` 
set -g base-index 1

# set-option -g default-terminal "screen-256color"
set-option -g mouse-select-pane on
set-option -g status-keys vi
set-option -g bell-action any
set-option -g set-titles on
set-option -g set-titles-string '#H:#S.#I.#P #W #T' # window number,program name,active (or not)
set-option -g visual-bell on

setw -g mode-keys vi
setw -g mode-mouse on
setw -g monitor-activity on

bind e previous-window
bind f next-window
bind j up-pane
bind k down-pane

set-option -g status-utf8 on
# set-option -g status-justify centre
set-option -g status-justify left
set-option -g status-bg black
set-option -g status-fg white
set-option -g status-left-length 40

set-option -g pane-active-border-fg green
set-option -g pane-active-border-bg black
set-option -g pane-border-fg white
set-option -g pane-border-bg black

set-option -g message-fg black
set-option -g message-bg green

#setw -g mode-bg black

setw -g window-status-bg black
setw -g window-status-current-fg green
setw -g window-status-alert-attr default
setw -g window-status-alert-fg yellow

set -g status-left '#[fg=red]#h#[fg=green]:#[fg=white]#S #[fg=green]][#[default]'

# set -g status-right '#[fg=green]][#[fg=white] #T #[fg=green]][ #[fg=blue]%Y-%m-%d #[fg=white]%H:%M#[default]'
set -g status-right '#[fg=green]][ #[fg=blue]%Y-%m-%d #[fg=white]%H:%M#[default]'

set -g history-limit 4096

# `+r reloads the configuration, handy
bind r source-file ~/.tmux.conf